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	<title>Ales Rarus &#187; biology</title>
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		<title>Ales Rarus &#187; biology</title>
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	<itunes:summary>A Rare Bird, A Strange Duck, One Funky Blog</itunes:summary>
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	<itunes:author>Funky Dung</itunes:author>
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		<title>Concerns about Huckabee</title>
		<link>http://alesrarus.funkydung.com/archives/2661</link>
		<comments>http://alesrarus.funkydung.com/archives/2661#comments</comments>
		<pubDate>Sat, 22 Dec 2007 00:49:51 +0000</pubDate>
		<dc:creator>Jerry</dc:creator>
				<category><![CDATA[government, law, and politics]]></category>
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		<category><![CDATA[abortion]]></category>
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		<description><![CDATA[I at first found Mike Huckabee to be an interesting character, as a possible bright point in the dismal lineup of presidential candidates. Unfortunately, his character did not bear up well when I looked at him further, and I&#8217;m sorry to see that some bloggers like Rod Dreher still think he&#8217;s a viable politician or [...]]]></description>
			<content:encoded><![CDATA[I at first found Mike Huckabee to be an interesting character, as a possible bright point in the dismal lineup of presidential candidates. Unfortunately, his character did not bear up well when I looked at him further, and I&#8217;m sorry to see that some bloggers like <a href="http://www.realclearpolitics.com/articles/2007/12/mike_huckabees_legacy.html" title="RealClearPolitics - Articles - Mike Huckabee's Legacy">Rod Dreher</a> still think he&#8217;s a viable politician or sign of a genuine movement. This post is to show evidence that Mr. Huckabee would be a poor president.<br /><br /><span id="more-2661"></span>First, I should clarify that I find Mr. Huckabee a devout, genuine Christian. That said, there are no doubt many Christians who may beat me to Heaven, but cannot be entrusted with a Boy Scout troop, let alone with the United States. I have yet to find any real evidence that Mr. Huckabee is cut out for the latter position.<br /><br />Regarding his use of Christianity: I do not know if that <a href="http://www.nytimes.com/2007/12/19/us/politics/19adbox.html" title="http://www.nytimes.com/2007/12/19/us/politics/19adbox.html">&#8220;floating cross&#8221;</a> image was intentional. I don&#8217;t really care as I find it manipulative either way. If that ad was just a &#8220;merry Christmas&#8221; message, then why was it funded by Mr. Huckabee&#8217;s campaign (which is not flush with cash), and why was it only shown in early primary states: New Hampshire, Iowa, and South Carolina? S<br />Sir, we celebrate Christmas in Pennsylvania as well! Why did we not get your best wishes? Mr. Huckabee has done a lot of coasting on his Christianity, and this ad is a <a href="http://www.opinionjournal.com/columnists/pnoonan/" title="OpinionJournal - Peggy Noonan">particularly disingenuous example of that</a>.<br /><br />I have looked for signs of real substance in Mr. Huckabee, and have been worried by what I have found. For instance, in Iowa, a little girl asked him who his favorite author was. Huckabee said it was <a href="http://www.nytimes.com/2007/12/21/us/politics/21cnd-huckabee.html" title="http://www.nytimes.com/2007/12/21/us/politics/21cnd-huckabee.html">Dr. Seuss.</a><br /><br />Either this was an attempt to please the girl, which seems phony, or it is the mark of a rather stunted intellect in a 52 year old man. Neither sounds palatable after 7 years of President Bush. <br /><br />What makes this worse is the fact that this Dr. Seuss fan wants to enact <a href="http://www.mikehuckabee.com/?FuseAction=Issues.View&amp;Issue_id=7" title="Mike Huckabee for President - Issues">grand federal schemes for education</a> and already has a history of expanding governmental <a href="http://www.ronpaul2008.com/homeschoolers/" title="Homeschoolers for Ron Paul">control of homschooling</a>. Homeschoolers have a strong love affair with Huckabee; the sooner the rose-colored lenses come off, the better for everyone.<br /><br />But at least he could be better in foreign policy than Bush or Giuliani, right? So I would have thought, but I seem to be wrong. Mr. Huckabee has published a statement outlining his <a href="http://www.foreignaffairs.org/20080101faessay87112/michael-d-huckabee/america-s-priorities-in-the-war-on-terror.html" title="Foreign Affairs - America's Priorities in the War on Terror - Michael D. Huckabee">foreign policy</a>. The bland, unsupported generalizations sound like a high schooler&#8217;s essay&#8212;but this is at least an improvement over Dr. Seuss! Less promising is the <i>doubling</i> of the military budget and expanding the war to Pakistan. A blogger has already fisked this mess <a href="http://www.lewrockwell.com/blog/lewrw/archives/017788.html" title="http://www.lewrockwell.com/blog/lewrw/archives/017788.html">here.</a><br /><br />Mr. Huckabee has good intentions but a bloated, overly ambitious mess of a platform. He is an able demagogue, but as a statesman he has every sign of being a sort of Bush III in terms of expanding the war abroad while crippling us at home with further federal intrusions and spending. <br /><br />I would be glad to work with Mr. Huckabee if he were a pastor in some ministry to the poor, but I do not want to be led by him at any level of government.<br /><br />Technorati Tags: Huckabee, Ron Paul, Iraq, Pakistan, Floating Cross, Education<br /><img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2661&type=feed" alt="" />]]></content:encoded>
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		<title>Skin Cells induced to become embryonic-like cells</title>
		<link>http://alesrarus.funkydung.com/archives/2654</link>
		<comments>http://alesrarus.funkydung.com/archives/2654#comments</comments>
		<pubDate>Tue, 27 Nov 2007 01:16:06 +0000</pubDate>
		<dc:creator>Jerry</dc:creator>
				<category><![CDATA[science and technology]]></category>
		<category><![CDATA[biology]]></category>
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		<description><![CDATA[We now know more of the reason why Ian Wilmut left the human cloning research behind. Researchers from two labs (Yamanaka in San Fran. and Japan, Thomson in Madison)&#160; have induced mature somatic cells to become embryonic-like stem cells, matching all the experimental criteria for embryonic stem cells. This new class of stem cells is [...]]]></description>
			<content:encoded><![CDATA[We now know more of the reason <a href="http://alesrarus.funkydung.com/archives/2649">why Ian Wilmut left the human cloning research behind</a>. Researchers from two labs (<a href="http://en.wikipedia.org/wiki/Shinya_Yamanaka" title="Shinya Yamanaka - Wikipedia, the free encyclopedia">Yamanaka</a> in San Fran. and Japan, <a href="http://en.wikipedia.org/wiki/James_Thomson_%28cell_biologist%29" title="James Thomson (cell biologist) - Wikipedia, the free encyclopedia">Thomson</a> in Madison)&nbsp; have induced mature somatic cells to become embryonic-like stem cells, matching all the experimental criteria for embryonic stem cells. This new class of stem cells is called an inducible pluripotent stem cells (<a href="http://en.wikipedia.org/wiki/Induced_Pluripotent_Stem_Cell" title="Induced Pluripotent Stem Cell - Wikipedia, the free encyclopedia">iPS cells</a>). Both labs created these cells by using viruses to express key genes in the somatic cells.<br /><br /><span id="more-2654"></span>This built off of Shinya Yamanaka&#8217;s earlier work on mice&#8212;in parallel, James Thomson&#8212;who isolated human embryonic stem cells in 1998, starting this whole debate&#8212;also created iPS cells, using different cells and a different mix of genes. <br /><br />Many questions remain open: clearly, it would be best to avoid using viruses to transform these cells. One of the genes the Yamanaka lab used, c-myc, is an <a href="http://en.wikipedia.org/wiki/Oncogene" title="Oncogene - Wikipedia, the free encyclopedia">oncogene</a>, something that we&#8217;d rather avoid using! I&#8217;d be interested in using something like a <a href="http://en.wikipedia.org/wiki/Liposome" title="Liposome - Wikipedia, the free encyclopedia">liposome</a> loaded with <a href="http://en.wikipedia.org/wiki/MRNA" title="Messenger RNA - Wikipedia, the free encyclopedia">mRNA</a> for the key genes. There has been work on the genetic networks that maintain embryonic stem cell identity that may help that: use the mRNA to induce a transient shift in the right genes, and that may act as a switch to &#8220;turn on&#8221; the network, creating a stable iPS cell with no permanent genetic alternation.<br /><br />But this is wide open, and we still have adult stem cells providing great results. I am&nbsp; particularly glad to see that two labs co-discovered this. It means that the work is more solid, and it also means that a monopoly on patents is less likely to stifle research. Embryonic stem cell research has been slower than many would like for a number of reasons. Many blame Bush, but this is only part of the reason. Much of the problem has been that the patents that Dr. Thomson generated are wide-ranging and have been <a href="http://www.wesleyjsmith.com/blog/2007/11/patents-not-bush-real-impediment-to.html" title="Patents, Not Bush, The Real Impediment to ESCR Advances">mercilessly enforced by the Wisconsin Alumni Research Foundation</a>, which holds the patents. <br /><br />For those who want to know more, check out the Yamanaka materials at <a href="http://www.cellpress.com/misc/page?page=misc21" title="Tuesday 27 November 2007
         
      
   

	
				
				



  Yamanaka paper in Cell captivates the world">Cell Journal</a> and Thomson&#8217;s <a href="http://www.sciencemag.org/cgi/content/abstract/1151526" title="Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells -- Yu et al., 10.1126/science.1151526 -- Science">abstract at Science</a>. <br /><img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2654&type=feed" alt="" />]]></content:encoded>
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		<title>Ian Wilmut Scuttles Cloning Research</title>
		<link>http://alesrarus.funkydung.com/archives/2649</link>
		<comments>http://alesrarus.funkydung.com/archives/2649#comments</comments>
		<pubDate>Sat, 17 Nov 2007 15:48:41 +0000</pubDate>
		<dc:creator>Jerry</dc:creator>
				<category><![CDATA[science and technology]]></category>
		<category><![CDATA[biology]]></category>
		<category><![CDATA[pro-life]]></category>
		<category><![CDATA[stem cells cloning]]></category>

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		<description><![CDATA[You read it right the first time, folks. Ian Wilmut, the cloner of Dolly the sheep, is giving up on human cloning in favor of stem cell regression, wherein one takes an adult cell and reprograms it into becoming an embryonic-like stem cell. (A briefer overview can be seen here.)It looks like Dr. Hwang&#8217;s fraud [...]]]></description>
			<content:encoded><![CDATA[You read it right the first time, folks. <br /><br />Ian Wilmut, the cloner of Dolly the sheep, <a href="http://www.telegraph.co.uk/earth/main.jhtml?xml=/earth/2007/11/16/scidolly116.xml&amp;page=3" title="Error - Prolexic">is giving up on human cloning in favor of stem cell regression</a>, wherein one takes an adult cell and <a href="http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6WSN-4KM3YVR-1&amp;_user=10&amp;_coverDate=08%2F25%2F2006&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=bd1142a3e9cd2bdca68663959ad6d326" title="ScienceDirect">reprograms it into becoming an embryonic-like stem cell.</a> (A briefer overview can be seen <a href="http://www.nature.com/stemcells/2007/0706/070607/full/stemcells.2007.6.html" title="Nature Reports Stem Cells">here</a>.)<br /><br /><span id="more-2649"></span>It looks like Dr. Hwang&#8217;s fraud shook up Dr. Wilmut&#8217;s lab and they never quite got over that. And while Dr. Wilmut&#8217;s announcement came out on the heels of some monkey cloning work, where a rhesus monkey was cloned using a skill cell&#8212;this is the novelty, where clone was derived from an adult cell, not an embryonic stem cell. <br /><br />The article does a good job of pointing out the numbers needed to do that cloning:&nbsp; 304 eggs were needed to make 2 cloned embryonic stem cell lines, one of which had chromosomal abnormalities. The cloned embryos&#8217; quality was poor and attempts to implant them into a female to carry to term did not go over well: no pregnancy got to 25 days out of 77 tries.<br /><br />Short of the biological colonialism that <a href="http://www.wesleyjsmith.com/blog/2007/11/biotechnological-colonialism.html" title="Biotechnological Colonialism">Wesley Smith has spoken about</a>, I doubt that we&#8217;ll be able to cough up hundreds of eggs to do this sort of work on humans. While we could eventually (hypothetically speaking) get to an efficient cloning method, the <i>research</i> needed to get there would require truckloads of eggs. We would need to harvest the eggs for the research from (scant) volunteers or paid (most likely poor) women would have a huge price tag, and I doubt folks have the will to do that. Especially since we have other, better options, as Dr. Wilmut has determined for himself.<img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2649&type=feed" alt="" />]]></content:encoded>
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		<title>Sloppy Science Reporting and Cloning Research Update</title>
		<link>http://alesrarus.funkydung.com/archives/2588</link>
		<comments>http://alesrarus.funkydung.com/archives/2588#comments</comments>
		<pubDate>Sat, 24 Mar 2007 21:50:35 +0000</pubDate>
		<dc:creator>Jerry</dc:creator>
				<category><![CDATA[science and technology]]></category>
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		<description><![CDATA[The media has a long, long way to go in reporting science: &#8220;South Korea to resume human egg cloning&#8221;, trumpets the United Press International article.Umm, guys, the idea is to clone humans using eggs, but not to clone the eggs (or ova) themselves. In the defense of UPI, though, while the title is wrong, the [...]]]></description>
			<content:encoded><![CDATA[The media has a long, long way to go in reporting science: &#8220;<a href="http://www.upi.com/NewsTrack/Science/south_korea_to_resume_human_egg_cloning/20070323-031155-5096r/" title="http://www.upi.com/NewsTrack/Science/south_korea_to_resume_human_egg_cloning/20070323-031155-5096r/">South Korea to resume human egg cloning</a>&#8221;, trumpets the United Press International article.<br /><br />Umm, guys, the idea is to clone humans using eggs, but not to clone the eggs (or ova) themselves. In the defense of UPI, though, while the title is wrong, the article itself seems to that much right, in that they talking about cloning embryos. <br /><br />But whether or not one is talking about clones or eggs, the work can&#8217;t be said to &#8220;resume&#8221; since the previous work was a fraud. The article is incorrect when it states that South Korea is planning &#8220;&#8230;to resume experiments with cloned human embryos next year&#8230;&#8221; . <br /><br />There are no clones as of now, people! They are presumably resuming their <i>attempts</i> to clone, and ultimate do what <a href="http://en.wikipedia.org/wiki/Hwang_Woo-Suk" title="Hwang Woo-Suk - Wikipedia, the free encyclopedia">Dr. Hwang had fraudulently claimed to achieve.</a><br /><br />There is an interesting, and presumably correct detail in the article about the source of ova to be used for these experiments: only the leftover eggs from IVF work will be used from these experiments. That may prove problematic in that they will not be as healthy as ones taken directly from the woman for use in research&#8212;IVF eggs will have had more time to degrade before being worked on by the researchers. It&#8217;ll make an already hard task even more difficult, but this safeguard is not surprising in the wake of Dr. Hwang&#8217;s abuse of power of female employees and their &#8220;voluntary&#8221; egg donations.<br /><br /><img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2588&type=feed" alt="" />]]></content:encoded>
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		<title>NCBC Bioethics Challenge</title>
		<link>http://alesrarus.funkydung.com/archives/2578</link>
		<comments>http://alesrarus.funkydung.com/archives/2578#comments</comments>
		<pubDate>Wed, 31 Jan 2007 04:04:51 +0000</pubDate>
		<dc:creator>Jerry</dc:creator>
				<category><![CDATA[science and technology]]></category>
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		<description><![CDATA[The National Catholic Bioethics Center, which is notable for its training programs in healthcare ethics and its fine quarterly publication, has an anonymous donor who has issued a matching grant (the 2007 Challenge Fund) as the Center works to pay off the mortgage on its new office in Philadelphia. Your donations count double if you [...]]]></description>
			<content:encoded><![CDATA[The <a href="http://www.ncbcenter.org/" title="Welcome to The National Catholic Bioethics Center">National Catholic Bioethics Center</a>, which is notable for its training programs in healthcare ethics and its fine <a href="http://www.ncbcenter.org/ncbq.asp" title="NCBQ -">quarterly publication</a>, has an anonymous donor who has issued a <a href="https://www.informationsecured.com/ncbc2/ncbc_donation.asp">matching grant</a> (the 2007 Challenge Fund) as the Center works to pay off the mortgage on its new office in Philadelphia. Your donations count double if you mark off the box that says it&#8217;s for the challenge fund on the donation form.<br /><br />I&#8217;ve been a member for two years, and they&#8217;ve impressed me as technically proficient thinkers who are rigorous with the science, philosophy and theological problems underlying bioethics. If you, like my wife or myself, watched House, MD and were angered by how he handled that pregnant rape victim, give your upset a productive vent by making a donation in House&#8217;s name to the NCBC. <img src='http://alesrarus.funkydung.com/wordpress/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> <img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2578&type=feed" alt="" />]]></content:encoded>
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		<title>One of America&#8217;s Great Student Newspapers</title>
		<link>http://alesrarus.funkydung.com/archives/2576</link>
		<comments>http://alesrarus.funkydung.com/archives/2576#comments</comments>
		<pubDate>Thu, 25 Jan 2007 21:43:46 +0000</pubDate>
		<dc:creator>Funky Dung</dc:creator>
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		<description><![CDATA[The Pitt News bills itself as &#8220;one of Amercia&#8217;s great student newspapers&#8221;. If only it were. Then again, maybe it is. *shudder*
In the 11 years I&#8217;ve been in Pittsburgh, I&#8217;ve watched the quality of writing and journalistic integrity of the Pitt News wax and wane with the arrival and graduation of classes. When it&#8217;s good, [...]]]></description>
			<content:encoded><![CDATA[<p>The <a href="http://www.pittnews.com" title="Pitt News">Pitt News</a> bills itself as &#8220;one of Amercia&#8217;s great student newspapers&#8221;. If only it were. Then again, maybe it is. *shudder*</p>
<p>In the 11 years I&#8217;ve been in Pittsburgh, I&#8217;ve watched the quality of writing and journalistic integrity of the Pitt News wax and wane with the arrival and graduation of classes. When it&#8217;s good, it&#8217;s no worse than any other small paper. When it&#8217;s bad, it&#8217;s awful. Sadly, it&#8217;s been bad more often than it&#8217;s been good. There have been years when the only feature I looked forward to reading was the comics page. Some years even that sucked. I&#8217;ve read articles that would make the journalism department go apoplectic - if Pitt had a journalism dept.</p>
<p>In the last couple years, though, I think the paper inproved a great. Perhaps there was an editor that was more interested in relatively unbiased news than sensationalism and sex columns. Those halcyon days may be over, though. Observe exhibits A and B:</p>
<p><a href="http://media.www.pittnews.com/media/storage/paper879/news/2007/01/25/News/Prices.Up.For.Birth.Control-2676352.shtml?sourcedomain=www.pittnews.com&#038;MIIHost=media.collegepublisher.com" title="Prices up for birth control - News
				
				
				
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Pitt News">Prices up for birth control</a></p>

<blockquote><p>Joseph Mance remembers a time when packets of birth control pills cost $8 each. Today he is trying to spread the word to his student clientele that prices have hiked up once again, this time to the $40 range. &#8220;I hate telling these kids, &#8216;We&#8217;re raising your pill price,&#8217;&#8221; he said with a troubled look. &#8220;It&#8217;s like pulling a gun on them.&#8221;
</p></blockquote>

<p>Telling kids their birth control pills will cost more is &#8220;like pulling a gun on them&#8221;? First of all, if they&#8217;re kids, they&#8217;re too immature to be having sex. Secondly, what ever happened to advising people to keep their hormones in check? If expensive birth control is either going to majorly disrupt students&#8217; lives or result in a lot of unintended pregancies, Pitt has much biggers problems than government economic policies. Granted, the Pitt News can&#8217;t be faulted for Mance making an ass of himself by allowing himself to be quoted uttering that nonsense, but the article is entirely one-sided. The entire front-page piece is written from the point of view that the Deficit Reduction Act of 2005, which is responsible for the price hike, is a bad law, at least as it pertains to offering cheap birth control for the masses. Reporting on the price hike is just fine and a public service announcement, but the second half of the article pertains to the politics of birth control discounts, which should have been presented in a more balanced fashion.</p>

<p><a href="http://media.www.pittnews.com/media/storage/paper879/news/2007/01/25/Opinion/Gay-Sheep.Should.Look.To.Jesus.Not.Science.For.Cure-2676612.shtml?sourcedomain=www.pittnews.com&#038;MIIHost=media.collegepublisher.com" title="Gay sheep should look to Jesus, not science for cure - Opinion
				
				
				
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Pitt News">Gay sheep should look to Jesus, not science for cure</a></p>

<blockquote><p>&#8230;[S]cientists have attempted to change the sexual orientation of sheep to help farmers, who have accused gay sheep of causing them financial loss. The scientists gave the sheep injections, adjusting the hormone levels in their brains and, amazingly, some previously gay rams became attracted to female sheep. Naturally, the gay and lesbian community was not happy. Their fear is that this success could be a gateway to experiments involving human sexuality and may one day be used to &#8220;breed out&#8221; homosexuals entirely. Personally, I think this experiment is debauchery. The scientists responsible should be tarred and feathered - or maybe tarred and wooled. Altering sexuality is a very slippery slope. But it seems as though these  scientists have forgotten an important fact: If those sheep would just accept Jesus Christ as their personal savior, they could easily overcome their homosexuality.</p></blockquote>

<p>At least this tripe was printed as opinion rather than news. Still, any newspaper that would print this should be embarassed and ashamed. It&#8217;s a sophomoric attempt at satire of Christian bioethics that reads like a secular <a href="http://www.chick.com/" title="Chick Publications">Jack Chick</a>&#8217;s poor imitation of a &#8220;<a href="http://en.wikipedia.org/wiki/A_Modest_Proposal" title="A Modest Proposal - Wikipedia, the free encyclopedia">A Modest Proposal</a>&#8221;. The kind of Christian presented in this article is straw man. Sure, there are Christians like the charicature the author presents; after all, stereotypes don&#8217;t appear out of thin air. Still, the author needs to realize that we&#8217;re not all fans of the 700 Club, any more than all gays are fans of Will and Grace.</p>

<p>You don&#8217;t have to be Fred Phelps to think active homosexuality is wrong. You also don&#8217;t have to hate or fear science if you&#8217;re a Christian. Heck, <a href="http://alesrarus.funkydung.com/archives/2388">you can even believe that homosexuality has a biological component and still think it&#8217;s wrong to perform homosexual acts</a>.</p>

<p>Christianity aside, arguing that a disorder of lower animals is natural and therefore acceptable in humans is ridiculous. Lots of lower animals practice cannibalism and incest. Will it soon be PC to defend those behaviors?<?p>

<p>In summary, this article isn&#8217;t just bad satire, it&#8217;s ironically full of the kind of disgusting malice and prejudice that seems to have offended the author, and the ignorance and denial he specifically mentions.</p>

<p>Be sure to <a href="http://www.pittnews.com/contactinfo/" title="Pitt News">let the editor of the Pitt News know how you feel about these articles</a>. Regarding the latter, you might want to let <a href="http://www.aclj.org/" title="Object moved">ACLJ</a> and the <a href="http://www.catholicleague.org/" title="http://www.catholicleague.org/">Catholic League</a> know, too.</p><img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2576&type=feed" alt="" />]]></content:encoded>
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		<item>
		<title>False Doctrines:  Sola Lexio Torta Mea Scripturae</title>
		<link>http://alesrarus.funkydung.com/archives/2563</link>
		<comments>http://alesrarus.funkydung.com/archives/2563#comments</comments>
		<pubDate>Thu, 14 Dec 2006 20:44:41 +0000</pubDate>
		<dc:creator>Funky Dung</dc:creator>
				<category><![CDATA[science and technology]]></category>
		<category><![CDATA[biology]]></category>
		<category><![CDATA[Christianity]]></category>
		<category><![CDATA[evangelical]]></category>
		<category><![CDATA[heresy]]></category>
		<category><![CDATA[physics]]></category>
		<category><![CDATA[protestant]]></category>
		<category><![CDATA[scripture]]></category>
		<category><![CDATA[stupidity]]></category>
		<category><![CDATA[theology]]></category>

		<guid isPermaLink="false">http://alesrarus.funkydung.com/archives/2563</guid>
		<description><![CDATA[Rob of UnSpace asks:

There&#8217;s a popular doctrine in the churches today, although it is rejected by the leadership of most churches. This doctrine is based on falsehoods, causes non-Christians to reject Christianity, Christians to lose their faith, and causes its followers to lie? Judging by the fruits of this doctrine, would you say this is [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.unspace.net/2006/12/what-would-you-call-such-a-doctrine/" title="UnSpace - A Christian Living in a Post-Christian World       &amp;raquo; What Would You Call Such a Doctrine?">Rob of UnSpace asks</a>:</p>

<blockquote><p>There&#8217;s a popular doctrine in the churches today, although it is rejected by the leadership of most churches. This doctrine is based on falsehoods, causes non-Christians to reject Christianity, Christians to lose their faith, and causes its followers to lie? Judging by the fruits of this doctrine, would you say this is of God or of something else?
</p></blockquote>

<p>The particular doctrine he&#8217;s asking about is <a href="http://powerballplace.blogspot.com/2006/12/some-parents-feel-gender-identity-in.html#c116543524128363974" title="PowerBlog!: SOME PARENTS FEEL GENDER IDENTITY IN CHILDREN IS UNCLEAR">Creationism</a>. What are your thoughts?</p>
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		<slash:comments>17</slash:comments>
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		<title>Plan B: Literature Review (Part II)</title>
		<link>http://alesrarus.funkydung.com/archives/2452</link>
		<comments>http://alesrarus.funkydung.com/archives/2452#comments</comments>
		<pubDate>Mon, 23 Oct 2006 15:13:33 +0000</pubDate>
		<dc:creator>Funky Dung</dc:creator>
				<category><![CDATA[essays, editorials, fisks, and rants]]></category>
		<category><![CDATA[science and technology]]></category>
		<category><![CDATA[biology]]></category>
		<category><![CDATA[emergency contraception]]></category>
		<category><![CDATA[ethics]]></category>
		<category><![CDATA[levonorgestrel]]></category>
		<category><![CDATA[medicine]]></category>
		<category><![CDATA[Plan B]]></category>

		<guid isPermaLink="false">http://alesrarus.funkydung.com/archives/2452</guid>
		<description><![CDATA[The first post in this series can be found here.

Last time I looked at a couple literature reviews about the methods of action of Plan B emergency contraception (levonorgestrel, LNG). This time I&#8217;m presenting On the the mechanisms of action of short-term levonorgestrel administration in emergency contraception (Durand, et al., 2001)

Experimental Design

Forty-five healthy, surgically sterilized [...]]]></description>
			<content:encoded><![CDATA[<p>The first post in this series can be found <a href="http://alesrarus.funkydung.com/archives/2449">here</a>.</p>

<p>Last time I looked at a couple literature reviews about the methods of action of Plan B emergency contraception (levonorgestrel, LNG). This time I&#8217;m presenting <em>On the the mechanisms of action of short-term levonorgestrel administration in emergency contraception</em> (Durand, et al., 2001)</p><span id="more-2452"></span>

<p><strong>Experimental Design</strong></p>

<blockquote><p>Forty-five healthy, <a href="http://patients.uptodate.com/topic.asp?file=wom_issu/6214" title="http://patients.uptodate.com/topic.asp?file=wom_issu/6214">surgically sterilized</a> women, aged 29 years to 35 years old (mean age 31 years), with regular menstrual cycles (cycle lengths between 25 days and 32 days) were recruited for this study. None had used hormonal contraception or any other medication within 6 months prior to the study. Participants were in good health as determined by medical history, physical examination, and routine screening laboratory tests, including <a href="http://www.nlm.nih.gov/medlineplus/ency/article/003911.htm" title="MedlinePlus Medical Encyclopedia: Pap smear">Papanicolaou smear.</a> Body weight, height, and blood pressure of each participant were registered by one investigator. Participants were issued a menstrual calendar on which they recorded details of all bleeding episodes throughout the study.</p></blockquote>

<p>This bit tells us that were these women not surgically sterilized, we would have no reason to not expect that they were capable of both ovulation and, under the right circumstances, pregnancy.</p>

<blockquote><p>The study was conducted in two consecutive cycles. Cycle was defined as the time elapsed from the first day of a spontaneous menstrual bleeding until the day preceding the next menses.</p></blockquote>

<p>That is, cycles were defined symptomatically, not based on the mythical average 28-day cycle. Two cycles were tracked for each participant, control cycle in which no drug was administered and a treated cycle in which LNG was administered.</p>

<blockquote><p>All participants were admitted during the first 10 days of their menstrual cycle. Before the control cycle, women were randomly allocated into three different groups as follows: Group A women received two doses of 0.75 mg LNG (<a href="http://www.medsafe.govt.nz/Consumers/cmi/p/Postinor-2.htm" title="Consumer Medicine Information">Postinor</a>, <a href="http://www.richter.hu/RichterWebsite/" title="Richter Gedeon Rt">Gedeon Richter</a>, Budapest, Hungary) taken 12 h apart, with the first dose given on the morning of day 10 of the menstrual cycle; Group B women received the same dose of LNG immediately after positive <a href="http://www.webmd.com/hw/womens_conditions/hw8017.asp" title="http://www.webmd.com/hw/womens_conditions/hw8017.asp">LH</a> [luteinizing hormone] detection in urine; and Group C women received the same dose of LNG 48 h after positive detection of urinary LH.</p></blockquote>

<ul>	
<li>Group A received the drug on cycle day 10, regardless of when they ovulated.</li>
<li>Group B received the drug after the LH surge, which shortly precedes ovulation.</li>
<li>Group C received the drug 48 hours after the LH surge, i.e., presumably after ovulation has occurred.</li>
</ul>

<blockquote>
<p>During both cycles (control and treated), all women were asked to monitor urinary LH every morning, starting on the 11th day of the menstrual cycle until the presence of LH was detected. At this time, <a href="http://www.nlm.nih.gov/medlineplus/ency/article/003779.htm" title="MedlinePlus Medical Encyclopedia: Transvaginal ultrasound">transvaginal ultrasound</a> was performed daily until <a href="http://en.wikipedia.org/wiki/Ovarian_follicle" title="http://en.wikipedia.org/wiki/Ovarian_follicle">follicle</a> rupture (FR) was observed. This was established by the presence of at least three of the following findings: acute decrease in mean diameter or disappearance of the follicle, presence of thickened irregular borders, increased <a href="http://www.medcyclopaedia.com/library/glossaries/echogenicity.aspx" title="Medcyclopaedia - Echogenicity">echogenecity</a> within the follicle, and presence of free <a href="http://www.medterms.com/script/main/art.asp?articlekey=4017" title="http://www.medterms.com/script/main/art.asp?articlekey=4017">intraperitoneal</a> fluid [16]&#8230;</p>
</blockquote>

<p>The LH surge was used as an indicator of imminent ovulation. Ovulation was observed and timed via ultrasound. The determination that ovulation had occurred was made by observing the follicle (which had contained the ovum) get smaller, disappear, thicken, or show up more brightly in the image, or the presence of fluid in the abdominal cavity.</p>

<blockquote><p>Daily blood samples were obtained from the day of positive LH detection in urine until the day menses began&#8230;The main purpose for measuring serum LH was to precisely determine, rather than based only on urinary LH detection, the actual time at which LNG was administered during the menstrual cycle. Follicular phase was considered from the first day of bleeding until the day of maximum serum LH concentrations and the luteal phase from the next day of serum LH surge until the day before menses began.</p></blockquote>

<p>LH levels in urine served only as a rough indicator of the onset of ovulation. Blood tests were used to get a more precise indicator of cycle day. The first phase of the cycle, the follicular phase, was considered to be from the first day of menstrual bleeding until the day of the highest level of LH was measured in a blood sample.</p>

<blockquote><p>In addition, <a href="http://www.webmd.com/hw/healthy_women/hw4583.asp" title="http://www.webmd.com/hw/healthy_women/hw4583.asp">endometrial biopsies</a> were taken from all participants during both control and treated cycles on day LH + 9. This day lies within the implantation window, the time during which the endometrium has optimal receptivity to implantation&#8230;</p>

<p>[&#8230;]</p>

<p>Endometrial morphology was assessed by correlating the chronological date (day after LH surge) with the morphological endometrial characteristics of specimens as an indicator of hormone action. The dating of the endometrium was related to the serum LH surge, FR, and luteal concentrations of E<sub>2</sub> [estrogen] and P<sub>4</sub> [progesterone], rather than to the “ideal” 28-day cycle, as previously described [22]. The parameters examined were number of glands, stromal edema, and predecidual changes as evaluated by the presence of prominent spiral arteries&#8230;</p></blockquote>

<p>On the ninth day of the <a href="http://www.ovulation-calendar.com/hlp-d04-luteal-phase.html" title="Ovulation Calendar - Luteal Phase">luteal phase</a>, a sample of the uterine lining was taken in order to access its receptivity to implantation (had there been an embryo implant).</p>

<blockquote><p>Timing comparisons between serum with urinary LH demonstrated inconsistencies in 12 out of 90 studied cycles (13.3%). In four control cycles (8.8%) and eight treated cycles (17.7%), urinary LH did not correlate with the day of maximum concentrations of serum LH. In these cases, serum LH, along with E<sub>2</sub> and P<sub>4</sub> concentrations, were used rather than urinary LH for cycle dating. Thus, eight participants during the treated cycle were identified as not corresponding to the originally assigned groups. Therefore, in four participants originally included in Group B and four in group C, the administration of LNG took place 3 &#177; 1 day prior to serum LH surge and were reassigned into a new group (group D). This new group received LNG during the late follicular phase, a few days prior to the occurance of LH surge. Thus, the groups studied consisted finally of 15 participants in Group A, 11 in groups B and C, and 8 in Group D.</p></blockquote>

<p>Like I said, urine LH level is just a rough indicator. As such, it led to premature administration of LNG in 8 cases.  Rather than waste data, a fourth study group was formed.</p>
<img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2452&type=feed" alt="" />]]></content:encoded>
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		<item>
		<title>Paging Mustapha Mond</title>
		<link>http://alesrarus.funkydung.com/archives/2505</link>
		<comments>http://alesrarus.funkydung.com/archives/2505#comments</comments>
		<pubDate>Thu, 21 Sep 2006 19:33:28 +0000</pubDate>
		<dc:creator>Funky Dung</dc:creator>
				<category><![CDATA[science and technology]]></category>
		<category><![CDATA[biology]]></category>
		<category><![CDATA[ethics]]></category>
		<category><![CDATA[eugenics]]></category>
		<category><![CDATA[medicine]]></category>
		<category><![CDATA[pro-life]]></category>
		<category><![CDATA[stupidity]]></category>

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		<description><![CDATA[Increasingly, Couples Use Embryo Screening &#160;  &#34;More and more couples are turning to an embryo-screening technique that allows them to choose the genetic makeup of their children, according to a survey released yesterday in the online edition of the journal Fertility and Sterility.&#34;  &#34;Son, we love you, especially since you turned out just [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.washingtonpost.com/wp-dyn/content/article/2006/09/20/AR2006092001652.html" title="Increasingly, Couples Use Embryo Screening - washingtonpost.com">Increasingly, Couples Use Embryo Screening</a> &nbsp;</p> <blockquote> <p>&quot;More and more couples are turning to an embryo-screening technique that allows them to choose the genetic makeup of their children, according to a survey released yesterday in the online edition of the journal Fertility and Sterility.&quot;</p> </blockquote> <p>&quot;Son, we love you, especially since you turned out just like the clinic  promised you would.&quot;</p> <p>Oh brave new world, that hath such people in&#39;t&#8230;*shudder*&nbsp;</p>  <img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2505&type=feed" alt="" />]]></content:encoded>
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		</item>
		<item>
		<title>Feed Me, Bitterman!</title>
		<link>http://alesrarus.funkydung.com/archives/2455</link>
		<comments>http://alesrarus.funkydung.com/archives/2455#comments</comments>
		<pubDate>Mon, 18 Sep 2006 16:41:46 +0000</pubDate>
		<dc:creator>Bitterman</dc:creator>
				<category><![CDATA[humor and oddities]]></category>
		<category><![CDATA[science and technology]]></category>
		<category><![CDATA[biology]]></category>
		<category><![CDATA[random odd thoughts]]></category>

		<guid isPermaLink="false">http://alesrarus.funkydung.com/archives/2455</guid>
		<description><![CDATA[ I now have a venus flytrap. I love these things. Imagine: a plant so hateful that it felt the need to evolve a way to trap and kill animals. What stories would it tell us if it could speak? What blasphemous litany would it write? This plant refused to allow its vegetative nature to [...]]]></description>
			<content:encoded><![CDATA[ <p>I now have a venus flytrap.</p> <p>I love these things. Imagine: a plant so hateful that it felt the need to evolve a way to trap and kill animals. What stories would it tell us if it could speak? What blasphemous litany would it write? This plant refused to allow its vegetative nature to limit it. The venus flytrap overcame its base nature and raised itself unto the position of carnivore. No victim, that plant. I&#39;m sure it&#39;s only the first step. Give these guys a few million years, and they&#39;ll be eating small rodents. Now that I&#39;d like to see.</p> <p>My new plant requires a name. Henceforth, let it be known as Steve.</p> <p>I&#39;m thinking about designing an experiment to determine if Steve can eat french fries. The way I figure, plants don&#39;t have hearts. What&#39;s cardiac disease to them? Just think, there could be a form of life that can eat french fries all day and suffer no detrimental health effects.</p> <p>The venus flytrap could well be the ultimate form of life.</p>  <img src="http://alesrarus.funkydung.com/wordpress/?ak_action=api_record_view&id=2455&type=feed" alt="" />]]></content:encoded>
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